Risk Assessment for Biocides

Example calculation for worker exposure for different substance types, intended uses and product types

• Definition of intended uses, relevant paths of exposure
• Different types of active substances
• Systemic vs. local assessment
• (Semi-)quantitative vs. qualitative assessment

Maren Lillich

Senior Manager Regulatory Affairs European Registered Toxicologist (ERT), spectra Consult, Germany

Katharina Gläser

Manager Regulatory Affairs Biocides Toxicology, Human Health Risk Assessment, SCC Scientific Consulting Company GmbH

• ECHA Guidance on the BPR, Volume III, Assessment & Evaluation (Parts B + C)
• Biocides Human Health Exposure Methodology, HEAdhoc Recommendations, HEEG Opinions, TAB
• ConsExpo Fact Sheets
• ARTFood, DRAWG guidance
• Guidance on Substances of Concern
• ECHA Guidance on the BPR, Volume V, Guidance on Disinfection by-Products
• ECHA template for Product Assessment Report

• TNsG models (2002, 2007), User Guidance (2002)
• BEAT
• ConsExpo
• ART
• Generic models
• RISKofDERM
• BfR Livestock Exposure Calculator
• BfR Calculator for estimating transfer of biocide residues into foods (non-prof. uses)

• Deriving scenarios from intended uses
• Selection of relevant models
• Refinement options

Training session: exposure assessment

Example calculation for worker exposure for different substance types, intended uses and product types

• Deduction of systemic and local reference values
• Risk characterisation for human health

• Deriving scenarios from intended uses
• Selection of relevant models and approaches
• Refinement options
• Example calculation for livestock and dietary exposure for different substance types, intended uses and product types