Programme

  1. Introduction to day two

    • Review of the previous day and introduction to the themes for the day
    Laura Robinson Laura Robinson
    Occupational Toxicologist, Toxicology Consulting Ltd, UK
    Mark Selby Mark Selby
    Director, Denehurst Chemical Safety Ltd, UK
  2. Recap of previous day

    • Reminder of data requirements and basics of a risk assessment
  3. Introductions and formal start of Day 2

  4. Physico-chemical data and importance in portioning and exposure estimation

    • Relevance of physico-chemical data and chemical structure assessments
    • Predictions based on chemistry
    • Chemical degradation and dissociation
  5. Interpretation of toxicity data to provide link to metabolism

    • Acute and repeat toxicity data
    • Indicators of dermal exposure
    • Indicators of metabolic processes
    • Significant of target organs
  6. Refreshment break

  7. Environmental data

    • Significance of biodegradation curves
    • Assessment of food chain concerns
  8. Risk characterisation and risk-benefit

    • Introduction of level of risk
    • Risk management options
    • Socio-economic and acceptable risks
    • Controls
    • Introduction to the group work scenario
  9. Introduction to Group Work

    • Setting up groups
    • Introduction to the first break (hand-outs and instructions)
    • Initial break-out session
  10. Lunch

  11. Group Work

    • Interactive process with break-out session and convening 'meetings', with course tutors providing support
  12. Refreshment break

  13. Group Work

    • Interactive process with break-out session and convening 'meetings', with course tutors providing support
  14. Questions

  15. Close

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