Explore the basics of reproductive and developmental toxicology

Many of the data gaps that have been identified during the implementation of REACH have been related to reproductive and developmental toxicity. However, it is also an important requirement for other regulatory compliance areas, including the Biocidal Products Regulation.

A unique feature of this training webinar is that, due to a strict limit of 25 delegates, you are encouraged to 'raise your hand' and put questions forward throughout the training – just as you would in a classroom environment.

By the end of the webinar, attendees will be able to:

  • Explain the difference between reproductive and developmental toxicity
  • Outline the ways in which chemical exposure may interfere with the normal reproductive and developmental processes
  • Describe the key elements of the male and female reproductive system
  • Outline the role hormones play in the reproductive process (endocrine system)
  • Define the terms endocrine disruptor, endocrine active substance, possible endocrine disruptor
  • Explain the criteria which are currently used for the identification of endocrine disruptors
  • Explain the process of fertilisation and the difference between embryonic and foetal stages
  • Explain why organogenesis is such a critical time period in the developmental process
  • Explain the difference between teratogen, congenital malformation and teratology and what is meant by maternal mediated effects
  • Outline how a thorough introduction to reproductive and developmental toxicity,and the current approach which is taken in their assessment (QSAR, human evidence, in vitro, in vivo studies - one generation, two generation, extended one generation reproductive toxicity studies and prenatal developmental toxicity studies)
  • Explain what is meant by delayed ossification, wavy ribs and malformations

Your expert coach

Laura Robinson is a qualified toxicologist and chemist with over ten years' experience in health, safety and environmental issues, as well as chemical compliance.

Laura is an accomplished toxicology trainer, consultant and author of two books on toxicology, published by Blackwell. Her third book, ‘A Practical Guide to Toxicology and Human Health Risk Assessment' (John Wiley & Sons) will be published in autumn 2018.